Halcinonide
is a corticosteroid adumbrated for the abatement of the anarchic and pruritic
manifestations of corticosteroid-responsive dermatoses, and is broadcast as a
chrism and ointment. Halcinonide is marketed beneath the cast name Halog® by
Ranbaxy Laboratories Inc. Analysis suggests that clobetasol propionate
demonstrates above pharmacologic ability in the analysis of crawling if
compared to halcinonide.
The
absolute apparatus of activity of contemporary corticosteroids is unclear.
However they acquire anti-inflammatory, antipruritic, and vasoconstrictive
actions. New analysis indicates that halcinonide activates MBP (myelin basal
protein) announcement via smoothened receptor activation. This award suggests
that halcinonide could be used in the analysis of assorted sclerosis analysis
as an another to Dexamethasone or Methylprednisolone.
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