CAS: 768-94-5
Molecular
Formula: C10H17N
Molecular
weight:151.24868
Amantadine
is a constructed tricyclic amine with antiviral, antiparkinsonian, and
antihyperalgesic activities. Amantadine appears to apply its antiviral
aftereffect adjoin the affliction A virus by interfering with the action of the
transmembrane area of the viral M2 protein, thereby preventing the absolution
of communicable viral nucleic acids into host cells. Furthermore, this abettor
prevents virus accumulation during virus replication. Amantadine exerts its
antiparkinsonian furnishings by aesthetic the absolution of dopamine from
striatal dopaminergic assumption terminals and inhibiting its pre-synaptic reuptake.
This abettor may aswell apply some anticholinergic aftereffect through
inhibition of N-methyl-D-aspartic acid (NMDA) receptor-mediated dispatch of
acetylcholine, consistent in antihyperalgesia.
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