Thursday, November 27, 2014

What is Podophyllotoxin?

Synonyms:(5R,5aR,8aR,9R)-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-5,8,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(5aH)-one
Formula:C22H22O8
Mol. mass:414.405 g/mol
assay :98%
Melting Point:183-184 °C (lit.)
Boiling Point:~597.9 °C at 760 mmHg (Predicted)
Density:~1.4 g/cm3 (Predicted)
Refractive Index:n20D 1.61 (Predicted)
storage temp. :2-8°C
Solubility:Soluble in 100 % ethanol, chloroform, acetone, water (0.12 mg/ml), and methanol.
Application:

A potent inhibitor of microtubule assembly and DNA topoisomerase II
more about:
http://www.bkherb.com/HerbalExtracts/Podophyllotoxin/

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