Acitretin
is an orally-active metabolite of the constructed ambrosial retinoic acid
abettor etretinate with abeyant antineoplastic, chemopreventive, anti-psoratic,
and embryotoxic properties. Acitretin activates nuclear retinoic acid receptors
(RAR), consistent in consecration of corpuscle differentiation, inhibition of
corpuscle proliferation, and inhibition of tissue aggression by anarchic cells.
This abettor may aswell arrest bump angiogenesis.
Acitretin
is a retinoid. Retinoids accept a anatomy agnate to vitamin A and are complex
in the accustomed advance of derma cells. Acitretin works by inhibiting the
boundless corpuscle advance and keratinisation (process by which derma beef
become thickened due to the degradation of a protein aural them) apparent in
psoriasis. It accordingly reduces the agglomeration of the skin, applique
accumulation and scaling.
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