Deoxycorticosterone acetate is white crystal powder,and it is odorlessness and insipidity.And it is quite stable in air ,and it is hardly soluble in water. Deoxycorticosterone acetate is widely used in many fields.As we all know,it is used as a intermediate,and it has other applications.
Deoxycorticosterone acetate white acicular crystal powder, its melting point is 154-160℃.It is easily soluble in ethanol,ethyl ether,methanol,acetone,,propylene glycol and vegetable oil. Deoxycorticosterone acetate should be sealed to preserve.It is used in biochemical study.As a matter of fact, deoxycorticosterone acetate is adrenal cortical hormone drug,so it has anti-inflammatory, allergy functions. Progestin is happened with cao and iodine in THF and methanol mixture solution,then, again with acetic acid potassium in anhydrous acetone reaction into ester,at last,the finished product is produced after purification. Deoxycorticosterone acetate has effect to the rats,because it can produce the hypertension in it.So,this product is a good drug to humans and animals.
Deoxycorticosterone acetate has many differences with deoxycorticosterone. Deoxycorticosterone is a steroid hormone produced by the adrenal gland.It is acts as a precursor to aldosterone.What’s a pity that it has no glucocorticoid activity.As we know,it is not a secretory hormone. Deoxycorticosterone can stimulate the collecting tubules to continue to excrete potassium.And it is a white flaky crystal,it is also easily soluble in ethanol and acetone,and it is easily soluble in water. Deoxycorticosterone has a point which is the some as the deoxycorticosterone acetate.The reason why I say so is that deoxycorticosterone is used as in biochemical study. It is also used to treat symptoms of adrenal insufficiency. This steroid hormone can suppresse seizures in humans ,at the same time ,this effect is the same in animals. If you take it too much,the effect of it will become sedation and ataxia.At surprise,the indomethacin can’t suppress the deoxycorticosteronem,and it can block the conversion of DHDOC into THDOC.As we all know,the DHDOC and THDOC were anticonvulsants.As a matter of fact,the deoxycorticosterone hasn’t anticonvulsant effects,but its primary and secondary metabolites has anticonvulsant effects. Deoxycorticosterone is mainly used to regulate electrolytes.While, Deoxycorticosterone acetate hasn’t this function. 11-Deoxycorticosterone can be produced from progesterone.On the whole,the feedback of deoxycorticosterone is the same as aldosterone which is respected to potassium.In my opinion,the risk serum potassium can cause a rise DOC secretion.When aldosterone depends on angiotensin II,the doctor should use the deoxycorticosterone to inhibit aldosterone. Steroid hormone acts as a hormone. Steroid hormone has many effects,it can help control metabolism and inflammation.In my opinion,the natural steroid hormones are produced by cholesterol.However,the synthetic steroids are different from the natural ones.some of the synthetic steroids may be stronger than the natural ones,but some of them are not. Steroids and sterols can diffuse into the cytoplasm of target cells because of their lipid-soluble properties.In my opinion,acetate is usually a anion in biology,and it utilized by organisms. Acetate can build block for biosynthesis.
On the whole, Deoxycorticosterone acetate plays a important role in our daily life.For example,if you want to diminish inflammation,you can use it ;if you have allergy,you can also use the deoxycorticosterone acetate.As we all know,there are many people who have allergy,so , deoxycorticosterone acetate widely can be used by them.Most of all,if you work on the biochemical study,you may need to it ,because it is a good subject in biochemical study.In some cases, cortisol and deoxycorticosterone acetate have effects on brain amino acid and electrolyte metabolism.
Generally speaking, deoxycorticosterone acetate is a medicine,and it has anti-inflammatory and allergy functions,what’s more,it also is a adrenal cortical hormone drug,at the same time,it is used in biochemical study. Deoxycorticosterone acetate has so many applications,so,its sales is very good.It is gradually known and used by people.
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